CXIDB ID 196
Deposition Summary
Depositor: Egor Marin
Contact: [email protected]
Deposition date: 2022-08-15
Last modified: 2022-08-15
DOI: 10.11577/1881337
Publication Details
Title: Structural basis for receptor selectivity and inverse agonism in S1P5 receptors
Authors: Elizaveta Lyapina et al.
Journal: Nature Communications
Year: 2022
DOI: https://doi.org/10.1038/s41467-022-32447-1
Experimental Conditions
Method: Serial Femtosecond Crystallography
Sample: Human sphingosine-1-phosphate receptor 5 (S1P5) in complex with ONO-5430608 inverse agonist
Wavelength: 1.278 Å (9.7 keV)
Lightsource: PAL-XFEL
Beamline: NCI
Data Files
Raw Data: images/
Auxiliary Files
CrystFEL stream: stream_and_hkl_and_inputs.tar.gz (265.87 MB)

Description

This dataset contains a subset of raw diffraction images for the serial femtosecond crystallography data of S1P5-ONO-5430608 complex. The diffraction data contain a strong systematic background as described in Lyapina et al. No additional background subtraction was applied to the data. In order to avoid its effects, the background subtraction implemented in CrystFEL, was applied (–rings-grad subtraction).

The final stream, supplemented with this dataset, was obtained with:

indexamajig 0.8.0

Respectively, the hkl file was obtained with:

partialator 0.8.0

Licensed under the CC0 Public Domain Dedication Waiver.

Please give proper credit via citations according to established scientific practice.